In scientific research, when Lysine hydrochloride (the shape it is metabolized best from) is taken in concentrations of lower than 1250mg (2 x 625mg tablets) it has a restricted effect on the Herpes and chilly sore virus - and when taken at a daily dose larger than 3000mg it is proven to be doubtlessly unsafe.

The exception to the rule is the DOT1 family, members of which methylate K79 within the globular region of histone H3 and which are structurally not related to SET-domain proteins four - 6 Recent work suggests that SET-area-containing proteins methylate a few proteins along with histones (see later)